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Chronic myeloid leukemia
1 OMIM reference -
3 associated genes
262 connected diseases
No signs/symptoms info
Disease Type of connection
Precursor B-cell acute lymphoblastic leukemia
Precursor T-cell acute lymphoblastic leukemia
Acute myeloid leukemia with t(8;21)(q22;q22) translocation
Distal 22q11.2 microdeletion syndrome
Familial platelet syndrome with predisposition to acute myelogenous leukemia
Isolated delta-storage pool disease
Familial pancreatic carcinoma
B-cell chronic lymphocytic leukemia
Essential thrombocythemia
Giant cell glioblastoma
Gliosarcoma
Autosomal agammaglobulinemia
Noonan syndrome
Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)
Hereditary breast and ovarian cancer syndrome
Familial prostate cancer
Juvenile myelomonocytic leukemia
Papillary or follicular thyroid carcinoma
Young adult-onset Parkinsonism
Common variable immunodeficiency
Noonan syndrome-like disorder with juvenile myelomonocytic leukemia
Cerebellar ataxia - hypogonadism
Familial retinoblastoma
Monosomy 13q14
Unilateral retinoblastoma
Adrenocortical carcinoma
Li-Fraumeni syndrome
Papilloma of choroid plexus
Acute myeloid leukemia with t(8;16)(p11;p13) translocation
Acute myeloblastic leukemia with maturation
Aleukemic mast cell leukemia
Bullous diffuse cutaneous mastocytosis
Classic mast cell leukemia
Cutaneous mastocytoma
Gastrointestinal stromal tumor
Isolated bone marrow mastocytosis
Lymphoadenopathic mastocytosis with eosinophilia
Nodular urticaria pigmentosa
Piebaldism
Plaque-form urticaria pigmentosa
Pseudoxanthomatous diffuse cutaneous mastocytosis
Smouldering systemic mastocytosis
Systemic mastocytosis with an associated clonal hematologic non-mast cell lineage disease
Telangiectasia macularis eruptiva perstans
Typical urticaria pigmentosa
Short stature due to isolated growth hormone deficiency with X-linked hypogammaglobulinemia
Hereditary gingival fibromatosis
Hereditary breast cancer
Hereditary site-specific ovarian cancer syndrome
SHORT syndrome
Burkitt lymphoma
Mantle cell lymphoma
Rubinstein-Taybi syndrome due to EP300 haploinsufficiency
Berardinelli-Seip congenital lipodystrophy
Uveal coloboma - cleft lip and palate - intellectual deficit
Acute promyelocytic leukemia
17p13.3 microduplication syndrome
Distal 17p13.3 microdeletion syndrome
Miller-Dieker syndrome
Budd-Chiari syndrome
Familial thrombocytosis
Myelofibrosis with myeloid metaplasia
Polycythemia vera
Capillary malformation - arteriovenous malformation
Familial isolated dilated cardiomyopathy
Parkes Weber syndrome
Autosomal dominant spastic paraplegia type 13
Coffin-Siris syndrome
Cone rod dystrophy
Familial rhabdoid tumor
Megalencephaly - polymicrogyria - postaxial polydactyly - hydrocephalus
Pelizaeus-Merzbacher-like due to HSPD1 mutation
Autosomal dominant hypohidrotic ectodermal dysplasia
Complete androgen insensitivity syndrome
Familial hypospadias
Kennedy disease
Partial androgen insensitivity syndrome
Congenital fiber-type disproportion myopathy
MODY syndrome
Familial congenital mirror movements
Ataxia-telangiectasia
Ataxia-telangiectasia variant
Combined cervical dystonia
Familial medullary thyroid carcinoma
Hereditary sensory and autonomic neuropathy type 4
Hereditary sensory and autonomic neuropathy type 5
Primary peritoneal carcinoma
Trichothiodystrophy
Xeroderma pigmentosum complementation group B
Autosomal dominant nonsyndromic intellectual deficit
Craniopharyngioma
Desmoid tumor
Hepatocellular carcinoma, childhood-onset
Pilomatrixoma
Pyogenic arthritis - pyoderma gangrenosum - acne
Opsismodysplasia
Congenital bilateral absence of vas deferens
Cystic fibrosis
Familial cutaneous telangiectasia and oropharyngeal predisposition cancer syndrome
Hereditary chronic pancreatitis
Idiopathic bronchiectasis
Male infertility with normal virilization due to meiosis defect
Seckel syndrome
Aneurysm - osteoarthritis syndrome
Familial thoracic aortic aneurysm and aortic dissection
Rubinstein-Taybi syndrome due to 16p13.3 microdeletion
Rubinstein-Taybi syndrome due to CREBBP mutations
Acatalasemia
Autosomal dominant medullary cystic kidney disease with or without hyperuricemia
Dedifferentiated liposarcoma
Well-differentiated liposarcoma
Hereditary spherocytosis
Hypocalcemic vitamin D-resistant rickets
Acute megakaryoblastic leukemia without Down syndrome
Melanoma of soft part
Severe combined immunodeficiency due to DNA-PKcs deficiency
Autosomal recessive primary microcephaly
Cerebellar ataxia-deafness-narcolepsy syndrome
Combined immunodeficiency due to ZAP70 deficiency
Alobar holoprosencephaly
Lobar holoprosencephaly
Microform holoprosencephaly
Midline interhemispheric variant of holoprosencephaly
Semilobar holoprosencephaly
Septopreoptic holoprosencephaly
Immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome
Charcot-Marie-Tooth disease type 2B2
Hypohidrotic ectodermal dysplasia with immunodeficiency
Leukocyte adhesion deficiency type I
Early-onset autosomal dominant Alzheimer disease
Hereditary cerebral hemorrhage with amyloidosis, Arctic type
Hereditary cerebral hemorrhage with amyloidosis, Dutch type
Hereditary cerebral hemorrhage with amyloidosis, Flemish type
Hereditary cerebral hemorrhage with amyloidosis, Iowa type
Hereditary cerebral hemorrhage with amyloidosis, Italian type
Hereditary cerebral hemorrhage with amyloidosis, Piedmont type
X-linked agammaglobulinemia
Acute myeloid leukemia with CEBPA somatic mutations
Behavioral variant of frontotemporal dementia
Classical progressive supranuclear palsy
Combined immunodeficiency due to STK4 deficiency
Inherited acute myeloid leukemia
Progressive non-fluent aphasia
Progressive supranuclear palsy - corticobasal syndrome
Progressive supranuclear palsy - parkinsonism
Progressive supranuclear palsy - progressive non fluent aphasia
Progressive supranuclear palsy - pure akinesia with gait freezing
Semantic dementia
3M syndrome
Acrodysostosis
Acrodysostosis with multiple hormone resistance
Alveolar rhabdomyosarcoma
Amyotrophic lateral sclerosis
Anophthalmia / microphthalmia - esophageal atresia
Athyreosis
Atypical Rett syndrome
Atypical teratoid tumor
Autoimmune lymphoproliferative syndrome
Autoimmune polyendocrinopathy type 1
Autosomal dominant Charcot-Marie-Tooth disease type 2M
Autosomal dominant centronuclear myopathy
Autosomal dominant intermediate Charcot-Marie-Tooth disease type B
Autosomal dominant polycystic kidney disease type 1 with tuberous sclerosis
Autosomal recessive systemic lupus erythematosus
Benign familial chorea
Blepharophimosis-intellectual deficit syndrome, SBBYS type
Brain-lung-thyroid syndrome
Brugada syndrome
CADASIL
Charcot-Marie-Tooth disease type 4F
Choreoacanthocytosis
Chronic intestinal pseudoobstruction
Classic multiminicore myopathy
Colobomatous microphthalmia
Congenital glaucoma
Congenital short bowel syndrome
Congenital stationary night blindness
Congenital valvular dysplasia
Craniofacial-deafness-hand syndrome
Dejerine-Sottas syndrome
Desmin-related myopathy with Mallory body-like inclusions
Distal myopathy with posterior leg and anterior hand involvement
Donnai-Barrow syndrome
Ear-patella-short stature syndrome
Ehlers-Danlos syndrome with periventricular heterotopia
Extraskeletal myxoid chondrosarcoma
Familial idiopathic steroid-resistant nephrotic syndrome with focal segmental hyalinosis
Familial multiple meningioma
Familial sick sinus syndrome
Fanconi anemia
Fetal akinesia-cerebral and retinal hemorrhage syndrome
Frontometaphyseal dysplasia
Genitopatellar syndrome
Glaucoma secondary to spherophakia / ectopia lentis and megalocornea
Idiopathic CD4 lymphocytopenia
Immunodeficiency due to a late component of complements deficiency
Infantile autosomal recessive medullary cystic kidney disease
Infantile myofibromatosis
Inherited cancer-predisposing syndrome due to biallelic BRCA2 mutations
Inherited congenital spastic tetraplegia
Isolated anophthalmia - microphthalmia
Isolated brachycephaly
Isolated plagiocephaly
Leigh syndrome with nephrotic syndrome
Lethal congenital contracture syndrome type 2
MMEP syndrome
Mandibular hypoplasia-deafness-progeroid syndrome
Monosomy 22q13
Muscle filaminopathy
Nager syndrome
Neurofibromatosis type 3
Osteodysplasty, Melnick-Needles type
Otopalatodigital syndrome type 1
Otopalatodigital syndrome type 2
Periventricular nodular heterotopia
Renal-hepatic-pancreatic dysplasia
Rigid spine syndrome
Sanfilippo syndrome type D
Septo-optic dysplasia
Tay-Sachs disease, B variant, adult form
Tay-Sachs disease, B variant, infantile form
Tay-Sachs disease, B variant, juvenile form
Tay-Sachs disease, B1 variant
Terminal osseous dysplasia - pigmentary defects
Thyroid hypoplasia
Van den Ende-Gupta syndrome
Waardenburg syndrome type 1
Waardenburg syndrome type 3
Weill-Marchesani syndrome
West syndrome
Williams syndrome
Multiple endocrine neoplasia type 1
Multiple endocrine neoplasia type 4
Autosomal recessive centronuclear myopathy
Barth syndrome
Childhood-onset nemaline myopathy
Congenital myopathy with excess of thin filaments
Dyskeratosis congenita
Familial melanoma
Hoyeraal-Hreidarsson syndrome
Idiopathic aplastic anemia
Idiopathic pulmonary fibrosis
Intermediate nemaline myopathy
Left ventricular noncompaction
Severe congenital nemaline myopathy
Typical nemaline myopathy
Atypical hemolytic uremic syndrome with C3 anomaly
Cherubism
Complement component 3 deficiency
Diffuse cutaneous systemic sclerosis
Heritable pulmonary arterial hypertension
Hyperinsulinism due to HNF1A deficiency
Inflammatory myofibroblastic tumor
Intellectual deficit, X-linked, Turner type
LEOPARD syndrome
Limited cutaneous systemic sclerosis
Metachondromatosis
Monosomy 5p
Multiple myeloma
Translocation renal cell carcinoma
Xeroderma pigmentosum complementation group E
Amyotrophic lateral sclerosis-parkinsonism-dementia complex
Synonym(s):
- Chronic granulocytic leukemia
- Chronic myelogenous leukemia
Classification (Orphanet):
- Rare hematologic disease
- Rare oncologic disease
Classification (ICD10):
- Neoplasms -
Epidemiological data:
Class of prevalence: 1-9 / 100 000
Average age onset: adulthood
Average age of death: -
Type of inheritance: sporadic
External references:
1 OMIM reference -
No MeSH references
Gene symbol UniProt reference OMIM reference
ABL1 P00519189980
BCR P11274151410
RUNX1 Q01196151385
No signs/symptoms info available.